Prevalence, severity, and predictors of symptom burden among adolescents and young adults with cancer

Symptom burden in adolescents and young adults (AYA) with cancer is poorly characterized but impacts quality of life. AYA with cancer experience substantial symptom burden. Risk of death increased with symptom severity. Interventions targeting cancer fatigue and anxiety, and targeting AYA in lower-income neighborhoods, are likely to improve quality of life in this population.